Broadened and elevated humoral immune response to EBNA1 in pediatric multiple sclerosis.
نویسندگان
چکیده
منابع مشابه
EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-γ and IL-2
Symptomatic primary Epstein-Barr virus (EBV) infection and elevated humoral immune responses to EBV are associated with an increased risk of developing multiple sclerosis (MS). We explored mechanisms leading to this change in EBV-specific immunity in untreated patients with MS and healthy virus carriers matched for MS-associated HLA alleles. MS patients showed selective increase of T cell respo...
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ورودعنوان ژورنال:
- Neurology
دوره 71 13 شماره
صفحات -
تاریخ انتشار 2008